학력
· 2011. 전남대학교 동물자원과학과 농학사
· 2013. 전남대학교 동물미생물공학전공 농학석사
· 2016. 전남대학교 동물미생물공학전공 농학박사
· 2013. 전남대학교 동물미생물공학전공 농학석사
· 2016. 전남대학교 동물미생물공학전공 농학박사
경력
· 2020 ~ 현재 전북대학교 동물자원과학과 교수
· 2017 ~ 2020 펜실베니아주립대학 박사후 연구원
· 2016 ~ 2017 코넬대학교 박사후 연구원
· 2017 ~ 2020 펜실베니아주립대학 박사후 연구원
· 2016 ~ 2017 코넬대학교 박사후 연구원
담당교과
· 동물미생물학
· 프로바이오틱스개론및실험
· 유식품가공학및실험
· 미생물과면역학
· 동물미생물학특론
· 동물미생물스트레스반응학
· 발효식품학특론
· 식품안전위생학특론
· 유가공학특론
· 프로바이오틱스특론
· 프로바이오틱스개론및실험
· 유식품가공학및실험
· 미생물과면역학
· 동물미생물학특론
· 동물미생물스트레스반응학
· 발효식품학특론
· 식품안전위생학특론
· 유가공학특론
· 프로바이오틱스특론
연구분야
· 박테리아 스트레스 반응 및 휴면–재개 기전 연구 (in vivo / in vitro)
· 기능성 균주 발굴과 프로바이오틱스를 통한 장내 불균형(Dysbiosis) 조절 기전 연구
· 기능성 균주 발굴과 프로바이오틱스를 통한 장내 불균형(Dysbiosis) 조절 기전 연구
논문
· Fernández-García, L., Gao, X., Kirigo, J., Song, S., Battisti, M. E., Garcia-Contreras, R., ... & Wood, T. K. (2024). Single-cell analysis reveals that cryptic prophage protease LfgB protects Escherichia coli during oxidative stress by cleaving antitoxin MqsA. Microbiology Spectrum, 12(2), e03471-23.
· Kim, H., Oh, S., & Song, S. (2024). Lactobacillus persisters formation and resuscitation. Journal of Microbiology and Biotechnology, 34(4), 854.
· Fernández-García, L., Song, S., Kirigo, J., Battisti, M. E., Petersen, M. E., Tomás, M., & Wood, T. K. (2024). Toxin/antitoxin systems induce persistence and work in concert with restriction/modification systems to inhibit phage. Microbiology spectrum, 12(1), e03388-23.
· S Song, A Jeong, J Lim, BK Kim, DJ Park, S Oh (2023). Lactiplantibacillus plantarum L67 probiotics vs paraprobiotics for reducing pro‐inflammatory responses in colitis mice. International Journal of Dairy Technology 76 (1), 168-177
· S Song, TK Wood (2022) Manipulating indole symbiont signaling. Environmental Microbiology Reports 14 (5), 691-696
· S Song, E Semenova, K Severinov, L Fernández-García, MJ Benedik,(2022) CRISPR-Cas Controls Cryptic Prophages. International journal of molecular sciences 23 (24), 16195
· S Song, JS Kim, R Yamasaki, S Oh, MJ Benedik, TK Wood (2021). Escherichia coli cryptic prophages sense nutrients to influence persister cell resuscitation. Environmental microbiology 23 (11), 7245-7254
· S Song, TK Wood (2021). Waiting for Godot: response to ‘How dead is dead? Viable but non-culturable versus persister cells’ Environmental Microbiology Reports 13 (3), 246-247
· S Song, TK Wood (2021). Mostly dead and all dead: response to ‘what do we mean by viability in terms of “viable but non‐culturable cells”’ Environmental Microbiology Reports 13 (3), 253-254
· S Song, TK Wood (2021). Viable but non‐culturable cells’ are dead. Environmental microbiology 23 (5), 2335-2338
· S Song, TK Wood (2021). The Primary Physiological Roles of Autoinducer 2 in Escherichia coli Are Chemotaxis and Biofilm Formation. Microorganisms 9 (2), 386
· S Song, TK Wood (2021). Are we really studying persister cells?. Environmental Microbiology Reports 13 (1), 3-7
· G Park, S Song (2021). Eradicating Bacterial Persister Cells with Substituted Indoles to Reduce Antibiotic Resistance. Journal of Dairy Science and Biotechnology 39 (4), 145-156
· TK Wood, S Song (2020). Forming and waking dormant cells: The ppGpp ribosome dimerization persister model. Biofilm 2, 100018
· S Song, TK Wood (2020). A primary physiological role of toxin/antitoxin systems is phage inhibition. Frontiers in Microbiology 11, 1895
· S. Song, TK Wood (2020). Combatting persister cells with substituted indoles. Frontiers in Microbiology 11, 1565
· S Song, TK Wood (2020). Toxin/antitoxin system paradigms: toxins bound to antitoxins are not likely activated by preferential antitoxin degradation. Advanced biosystems 4 (3), 1900290
· S. Song, TK Wood (2020). Forming and Waking Dormant Cells: The ppGpp Ribosome Dimerization Persister Model. Biofilm. 2:100018
· S Song, TK Wood. (2020) ppGpp Ribosome Dimerization Model for Bacterial Persister Formation and Resuscitation. BBRC (doi.org/10.1016/j.bbrc.2020.01.102).
· R Yamasaki*, S Song*, M Benedik, T Wood. (2020) Persister Cells Resuscitate Using Membrane Sensors that Activate Chemotaxis, Lower cAMP Levels, and Revive Ribosomes. (*, Co-first author) iScience 23: 100792. (*,Co-first author)
· S Song, TK Wood. (2019) Persister Cells Resuscitate via Ribosome Modification by 23S rRNA Pseudouridine Synthase RluD. Under review after first revision, Environmental Microbiology (on-line). Highlighted TWIM episode #209
· W Zhang, R Yamasaki, S Song, TK Wood (2019) Interkingdom Signal Indole Inhibits Pseudomonas aeruginosa Persister Cell Waking. Journal of Applied Microbiology (on-line).
· S Song, T Gong, R Yamasaki, JS Kim, TK Wood (2019). Identification of a Potent Indigoid Persister Antimicrobial by Screening Dormant Cells. Biotechnology and Bioengineering 116(9), 2263-2274. Editor’s Choice
· S Song, Y Guo, JS Kim, X Wang, TK Wood (2019). Phages Mediate Bacterial Self Recognition. Cell Reports 27 (3), 737-749.
· TK Wood, S Song, R Yamasaki (2019). Ribosome dependence of persister cell formation and resuscitation. Journal of Microbiology 57 (3), 213-219.
· JS Kim, R Yamasaki, S Song, W Zhang, TK Wood (2018). Single cell observations show persister cells wake based on ribosome content. Environmental Microbiology 20(6) 2085-2098.
· Y Lee*, S Song*, L Sheng, L Zhu, JS Kim, TK Wood (2018). Substrate Binding Protein DppA1 of ABC Transporter DppBCDF Increases Biofilm Formation in Pseudomonas aeruginosa by Inhibiting Pf5 Prophage Lysis. Frontiers in Microbiology 9, 30. (*,Co-first author)
· S Song, TK Wood (2018). Post-Segregational Killing and Phage Inhibition Are Not Mediated by Cell Death Through Toxin/Antitoxin Systems. Frontiers in Microbiology 9, 814.
· L Zhu, VG Poosarla, S Song, TL Wood, DS Miller, B Yin, TK Wood (2018). Glycoside Hydrolase DisH from Desulfovibrio vulgaris Degrades the N‐Acetylgalactosamine Component of Diverse Biofilms. Environmental Microbiology 20, 2026–2037.
· M Pu, L Sheng, S Song, T Gong, TK Wood (2018). Serine Hydroxymethyltransferase ShrA (PA2444) Controls Rugose Small-Colony Variant Formation in Pseudomonas aeruginosa. Frontiers in Microbiology 9, 315.
· JS Kim, AB Schantz, S Song, M Kumar, TK Wood (2018). GhoT of the GhoT/GhoS toxin/antitoxin system damages lipid membranes by forming transient pores. Biochemical and Biophysical Research Communications 497 (2), 467-472.
· SS Park, YJ Lee, S Song, B Kim, H Kang, S Oh, E Kim (2018). Lactobacillus acidophilus NS1 attenuates diet-induced obesity and fatty liver. Journal of Endocrinology 237 (2), 87-100.
· Song, S., Lee, S. J., Park, D. J., Oh, S., Lim, K. T. (2016). The anti-allergic activity of Lactobacillus plantarum L67 ad its application to yogurt. J. Dairy Sci. 99: 9372-9382.
· Song, S., Oh, S., Lim, K. T. (2016) Probiotic Lactobacillus plantarum L67 has a protective character from cadmium chloride-stimulated raw 264.7 cells. J. Dairy Sci. 99:1812–1821.
· Lee, S. J. Lee, J. Song, S. Lim, K. T. (2016) Glycoprotein isolated from Styrax japonica Siebold et al. Zuccarini inhibits oxidative and pro-inflammatory responses in HCT116 colonic epithelial cells and dextran sulfate sodium-treated ICR mice. Food Chem. Toxicol. 87: 12-22.
· Song, S., Oh, S., Lim, K. T. (2015) The glycoprotein (18 kDa) isolated from Lactobacillus plantarum L67 suppressed β-hexosaminidase, histamine, and the expression of TNF-α and IL-4 in the BPA-stimulated RBL-2H3 cells. Process Biochem. 51: 105-112.
· Song, S., Oh, S., Lim, K. T. (2015) Bioactivity of proteins isolated from Lactobacillus plantarum L67 treated with Zanthoxylum Piperitum DC glycoprotein. Lett. Appl. Microbiol. 60: 597-604.
· . Song, S., Oh, S., Lim, K. T. (2015) The proteins (12 and 15kDa) isolated from heat-killed Lactobacillus plantarum L67 induces apoptosis in HT-29 cells. Cell Biochem. Func. 33: 89-96.
· Song, S., Bae, D. W., Lim, K., Griffiths, M. W. Oh, S. (2014) Cold stress improves the ability of Lactobacillus plantarum L67 to survive freezing. Int. J. Food Microbiol. 191: 135-143.
· Kim, H., Oh, S., & Song, S. (2024). Lactobacillus persisters formation and resuscitation. Journal of Microbiology and Biotechnology, 34(4), 854.
· Fernández-García, L., Song, S., Kirigo, J., Battisti, M. E., Petersen, M. E., Tomás, M., & Wood, T. K. (2024). Toxin/antitoxin systems induce persistence and work in concert with restriction/modification systems to inhibit phage. Microbiology spectrum, 12(1), e03388-23.
· S Song, A Jeong, J Lim, BK Kim, DJ Park, S Oh (2023). Lactiplantibacillus plantarum L67 probiotics vs paraprobiotics for reducing pro‐inflammatory responses in colitis mice. International Journal of Dairy Technology 76 (1), 168-177
· S Song, TK Wood (2022) Manipulating indole symbiont signaling. Environmental Microbiology Reports 14 (5), 691-696
· S Song, E Semenova, K Severinov, L Fernández-García, MJ Benedik,(2022) CRISPR-Cas Controls Cryptic Prophages. International journal of molecular sciences 23 (24), 16195
· S Song, JS Kim, R Yamasaki, S Oh, MJ Benedik, TK Wood (2021). Escherichia coli cryptic prophages sense nutrients to influence persister cell resuscitation. Environmental microbiology 23 (11), 7245-7254
· S Song, TK Wood (2021). Waiting for Godot: response to ‘How dead is dead? Viable but non-culturable versus persister cells’ Environmental Microbiology Reports 13 (3), 246-247
· S Song, TK Wood (2021). Mostly dead and all dead: response to ‘what do we mean by viability in terms of “viable but non‐culturable cells”’ Environmental Microbiology Reports 13 (3), 253-254
· S Song, TK Wood (2021). Viable but non‐culturable cells’ are dead. Environmental microbiology 23 (5), 2335-2338
· S Song, TK Wood (2021). The Primary Physiological Roles of Autoinducer 2 in Escherichia coli Are Chemotaxis and Biofilm Formation. Microorganisms 9 (2), 386
· S Song, TK Wood (2021). Are we really studying persister cells?. Environmental Microbiology Reports 13 (1), 3-7
· G Park, S Song (2021). Eradicating Bacterial Persister Cells with Substituted Indoles to Reduce Antibiotic Resistance. Journal of Dairy Science and Biotechnology 39 (4), 145-156
· TK Wood, S Song (2020). Forming and waking dormant cells: The ppGpp ribosome dimerization persister model. Biofilm 2, 100018
· S Song, TK Wood (2020). A primary physiological role of toxin/antitoxin systems is phage inhibition. Frontiers in Microbiology 11, 1895
· S. Song, TK Wood (2020). Combatting persister cells with substituted indoles. Frontiers in Microbiology 11, 1565
· S Song, TK Wood (2020). Toxin/antitoxin system paradigms: toxins bound to antitoxins are not likely activated by preferential antitoxin degradation. Advanced biosystems 4 (3), 1900290
· S. Song, TK Wood (2020). Forming and Waking Dormant Cells: The ppGpp Ribosome Dimerization Persister Model. Biofilm. 2:100018
· S Song, TK Wood. (2020) ppGpp Ribosome Dimerization Model for Bacterial Persister Formation and Resuscitation. BBRC (doi.org/10.1016/j.bbrc.2020.01.102).
· R Yamasaki*, S Song*, M Benedik, T Wood. (2020) Persister Cells Resuscitate Using Membrane Sensors that Activate Chemotaxis, Lower cAMP Levels, and Revive Ribosomes. (*, Co-first author) iScience 23: 100792. (*,Co-first author)
· S Song, TK Wood. (2019) Persister Cells Resuscitate via Ribosome Modification by 23S rRNA Pseudouridine Synthase RluD. Under review after first revision, Environmental Microbiology (on-line). Highlighted TWIM episode #209
· W Zhang, R Yamasaki, S Song, TK Wood (2019) Interkingdom Signal Indole Inhibits Pseudomonas aeruginosa Persister Cell Waking. Journal of Applied Microbiology (on-line).
· S Song, T Gong, R Yamasaki, JS Kim, TK Wood (2019). Identification of a Potent Indigoid Persister Antimicrobial by Screening Dormant Cells. Biotechnology and Bioengineering 116(9), 2263-2274. Editor’s Choice
· S Song, Y Guo, JS Kim, X Wang, TK Wood (2019). Phages Mediate Bacterial Self Recognition. Cell Reports 27 (3), 737-749.
· TK Wood, S Song, R Yamasaki (2019). Ribosome dependence of persister cell formation and resuscitation. Journal of Microbiology 57 (3), 213-219.
· JS Kim, R Yamasaki, S Song, W Zhang, TK Wood (2018). Single cell observations show persister cells wake based on ribosome content. Environmental Microbiology 20(6) 2085-2098.
· Y Lee*, S Song*, L Sheng, L Zhu, JS Kim, TK Wood (2018). Substrate Binding Protein DppA1 of ABC Transporter DppBCDF Increases Biofilm Formation in Pseudomonas aeruginosa by Inhibiting Pf5 Prophage Lysis. Frontiers in Microbiology 9, 30. (*,Co-first author)
· S Song, TK Wood (2018). Post-Segregational Killing and Phage Inhibition Are Not Mediated by Cell Death Through Toxin/Antitoxin Systems. Frontiers in Microbiology 9, 814.
· L Zhu, VG Poosarla, S Song, TL Wood, DS Miller, B Yin, TK Wood (2018). Glycoside Hydrolase DisH from Desulfovibrio vulgaris Degrades the N‐Acetylgalactosamine Component of Diverse Biofilms. Environmental Microbiology 20, 2026–2037.
· M Pu, L Sheng, S Song, T Gong, TK Wood (2018). Serine Hydroxymethyltransferase ShrA (PA2444) Controls Rugose Small-Colony Variant Formation in Pseudomonas aeruginosa. Frontiers in Microbiology 9, 315.
· JS Kim, AB Schantz, S Song, M Kumar, TK Wood (2018). GhoT of the GhoT/GhoS toxin/antitoxin system damages lipid membranes by forming transient pores. Biochemical and Biophysical Research Communications 497 (2), 467-472.
· SS Park, YJ Lee, S Song, B Kim, H Kang, S Oh, E Kim (2018). Lactobacillus acidophilus NS1 attenuates diet-induced obesity and fatty liver. Journal of Endocrinology 237 (2), 87-100.
· Song, S., Lee, S. J., Park, D. J., Oh, S., Lim, K. T. (2016). The anti-allergic activity of Lactobacillus plantarum L67 ad its application to yogurt. J. Dairy Sci. 99: 9372-9382.
· Song, S., Oh, S., Lim, K. T. (2016) Probiotic Lactobacillus plantarum L67 has a protective character from cadmium chloride-stimulated raw 264.7 cells. J. Dairy Sci. 99:1812–1821.
· Lee, S. J. Lee, J. Song, S. Lim, K. T. (2016) Glycoprotein isolated from Styrax japonica Siebold et al. Zuccarini inhibits oxidative and pro-inflammatory responses in HCT116 colonic epithelial cells and dextran sulfate sodium-treated ICR mice. Food Chem. Toxicol. 87: 12-22.
· Song, S., Oh, S., Lim, K. T. (2015) The glycoprotein (18 kDa) isolated from Lactobacillus plantarum L67 suppressed β-hexosaminidase, histamine, and the expression of TNF-α and IL-4 in the BPA-stimulated RBL-2H3 cells. Process Biochem. 51: 105-112.
· Song, S., Oh, S., Lim, K. T. (2015) Bioactivity of proteins isolated from Lactobacillus plantarum L67 treated with Zanthoxylum Piperitum DC glycoprotein. Lett. Appl. Microbiol. 60: 597-604.
· . Song, S., Oh, S., Lim, K. T. (2015) The proteins (12 and 15kDa) isolated from heat-killed Lactobacillus plantarum L67 induces apoptosis in HT-29 cells. Cell Biochem. Func. 33: 89-96.
· Song, S., Bae, D. W., Lim, K., Griffiths, M. W. Oh, S. (2014) Cold stress improves the ability of Lactobacillus plantarum L67 to survive freezing. Int. J. Food Microbiol. 191: 135-143.